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Jessica Pillard

Document Type


Publication Date



Natural Sciences

Faculty Advisor

Diane Ramos


Butterfly wings have become a common biological model used to
show how cells responds to different chemical signals, because adult wing
eyespots and the wing color pattern are determined by the cell interactions in
the epidermis. There are multiple signaling pathways that are used to transduce
the signal, one being the transforming growth factor-β (TGF-β)
pathway. An important morphogen signalling molecue of this pathway is
Decapentaplegic (Dpp), which has a role in the formation of the wing imaginal
disc in fruit flies. To test the role of Dpp in butterfly wing development,
wings of Vanessa cardui pupa were wounded and treated with a Dpp
inhibitor, SB431542 and subsequent development was monitored. These results
could give insight to butterfly wing formation, and a better understanding of
the role of Dpp.