Proteomic Approaches for Studying the Phases of Wound Healing
Studies in Mechanobiology, Tissue Engineering and Biomaterials
© 2009, Springer Berlin Heidelberg. Proteome level information is necessary to understand the function of specific cell types and their roles in health and disease. Proteomics is a rapidly developing field with a wide range of applications in wound healing. The ability to use proteomics to assess the wound healing process would have many benefits, including earlier evidence of healing and better understanding of how different treatments affect the wound at the protein level. The basis of what is known about the chronic wound proteome is based on results from a broad collection of studies utilizing a number of different proteomic techniques on fluids and tissues from wounds with different etiologies. The identification of biomarkers associated with healing or delayed healing in chronic wounds could have great significance in the use of current treatments, as well as in the development of new therapeutic interventions.
Acute Wound, Chronic Wound, Negative Pressure Wound Therapy, Pressure Ulcer, Venous Ulcer
Edsberg, Laura E., "Proteomic Approaches for Studying the Phases of Wound Healing" (2009). Articles & Book Chapters. 351.