Department
Health Promotion
Document Type
Article
Publication Source
Evidence-based Complementary and Alternative Medicine
Publication Date
2012-02-03
Volume
2012
Article Number
515893
Abstract
fMRI studies showed that acupuncture could induce hemodynamic changes in brain networks. Many of these studies focused on whether specific acupoints could activate specific brain regions and were often limited to manual acupuncture at acupoints on the limbs. In this fMRI study, we investigated acupuncture's modulation effects on brain functional networks by electroacupuncture (EA) at acupoints on the midline of abdomen. Acupoints Guanyuan (CV4) and Zhongwan (CV12) were stimulated in 21 healthy volunteers. The needling sensations, brain activation, and functional connectivity were studied. We found that the limbic-prefrontal functional network was deactivated by EA at CV4 and CV12. More importantly, the local functional connectivity was significantly changed during EA stimulation, and the change persisted during the period after the stimulation. Although minor differences existed, both acupoints similarly modulated the limbic-prefrontal functional network, which is overlapped with the functional circuits associated with emotional and cognitive regulation. Copyright © 2012 Jiliang Fang et al.
DOI
10.1155/2012/515893
Recommended Citation
Fang, Jiliang; Wang, Xiaoling; Liu, Hesheng; Wang, Yin; Zhou, Kehua; Hong, Yang; Liu, Jun; Wang, Lei; Xue, Chao; Song, Ming; Liu, Baoyan; and Zhu, Bing, "The limbic-prefrontal network modulated by electroacupuncture at CV4 and CV12" (2012). Articles & Book Chapters. 318.
https://digitalcommons.daemen.edu/faculty_scholar/318
https://doi.org/10.1155/2012/515893
Comments
© 2012 Jiliang Fang et al.
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.